Plasma p-tau217 and p-tau217/Aβ1–42 ratios associate with medial temporal lobe subfield atrophy in normal aging and mild cognitive impairment

Amirhossein Rabiei rad, Ali Nadaki, Farbod Khosravi, Hamide Nasiri, Arman Ghayourvahdat · 2025

Read Plasma p-tau217 and p-tau217/Aβ1–42 ratios associate with medial temporal lobe subfield atrophy in normal aging and mild cognitive impairment by Amirhossein Rabiei rad, Ali Nadaki, Farbod Khosravi, Hamide Nasiri, Arman Ghayourvahdat (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12824393.txt.

Description

Amirhossein Rabiei Rad and four co-authors, with a national Alzheimer's imaging initiative, present a 2025 study linking blood markers to shrinkage in the brain's memory hub. Blood tests for two tau related markers now promise early warning of Alzheimer's disease. How they tie to the fine subfields of the medial temporal lobe was unclear.

The team used data from 330 people with normal aging or mild thinking problems. They matched blood marker levels, and ratios between markers, with scan measures of each subfield's size. They also tested whether one marker carries the effect of another. The work aims to sharpen what a simple blood draw can say about brain change.

Catalog record

CREATORAmirhossein Rabiei rad, Ali Nadaki, Farbod Khosravi, Hamide Nasiri, Arman Ghayourvahdat
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE58 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12824393

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