Baseline and early changes in eosinophil count and neutrophil-to-eosinophil ratio predict outcomes in metastatic renal cell carcinoma treated with nivolumab
Ondřej Fiala, Katarína Rejleková, Tomas Buchler, Hana Študentová, Alexandr Poprach, Michal Vočka, Petr Hošek, Jindřich Kopecký, Martin Matějů, Anežka Zemánková, Martina Spisarová, Michaela Tkadlecová, Peter Priester, Jan Kouřil, Radka Lohynská, Lucie Grmelová, Alexander Savka, Katarína Štefániková, · 2025
Read Baseline and early changes in eosinophil count and neutrophil-to-eosinophil ratio predict outcomes in metastatic renal cell carcinoma treated with nivolumab by Ondřej Fiala, Katarína Rejleková, Tomas Buchler, Hana Študentová, Alexandr Poprach, Michal Vočka, Petr Hošek, Jindřich Kopecký, Martin Matějů, Anežka Zemánková, Martina Spisarová, Michaela Tkadlecová, Peter Priester, Jan Kouřil, Radka Lohynská, Lucie Grmelová, Alexander Savka, Katarína Štefániková, (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12824351.txt.
Description
Ondřej Fiala and co-authors look for simple blood signs that predict how kidney cancer patients fare on an immune drug in 2025. The drug is used when the cancer has spread. The team tracks one type of white blood cell and a ratio built from two types. Counts were taken at the start of care and one month in.
More than four hundred patients were in the study. Higher counts of that cell type linked to longer time without growth and longer life. A low ratio at one month also linked to better outcomes. Sharp moves in the ratio in the wrong way linked to worse outcomes. Response rates were higher in the same good sign groups. The tests are cheap and in routine use.
Catalog record
| CREATOR | Ondřej Fiala, Katarína Rejleková, Tomas Buchler, Hana Študentová, Alexandr Poprach, Michal Vočka, Petr Hošek, Jindřich Kopecký, Martin Matějů, Anežka Zemánková, Martina Spisarová, Michaela Tkadlecová, Peter Priester, Jan Kouřil, Radka Lohynská, Lucie Grmelová, Alexander Savka, Katarína Štefániková, |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |