Evaluation of alternative transfusion triggers in hemodynamically stable, non-ventilated cancer patients: a prospective observational study
Ardak Arynov, Johannes Gratz, Barbara Kabon, Dilyara Kaidarova, Alima Satanova, Evgeni Brotfain · 2025
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Description
Ardak Arynov and co-authors test whether a physiology measure beats hemoglobin alone in deciding who gains from a blood transfusion. They followed 107 stable cancer patients who all qualified for transfusion under a strict hemoglobin rule. Patients were split by their oxygen extraction ratio, a measure of how hard tissues pull oxygen from blood.
Those starting with high extraction improved far more after transfusion across every oxygen measure, despite similar hemoglobin levels and rises. Baseline hemoglobin barely tracked the response. The authors back individualized triggers, while calling for larger randomized trials to confirm safety.
Catalog record
| CREATOR | Ardak Arynov, Johannes Gratz, Barbara Kabon, Dilyara Kaidarova, Alima Satanova, Evgeni Brotfain |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |