Dietary duration and composition differentially influence mitochondrial activity and gene expression in a tissue-specific manner in aged rats
Brea J Ford, Anisha Banerjee, Sarah Ding, Anna A Caton, Ashley Grothaus, Sara N Burke, Abbi R Hernandez · 2025
Read Dietary duration and composition differentially influence mitochondrial activity and gene expression in a tissue-specific manner in aged rats by Brea J Ford, Anisha Banerjee, Sarah Ding, Anna A Caton, Ashley Grothaus, Sara N Burke, Abbi R Hernandez (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12823141.txt.
Description
Brea Ford and co-authors present a 2025 study of diet schedules and mitochondrial health in old rats. Three regimes were compared: eating windows long term, eating windows started late, and eating windows with a keto mix long term. Powerhouse activity and gene signals were read in brain, liver, and muscle.
Effects split by tissue and by diet in a tangled pattern. One energy step ran hot in the liver under long term keto windows. Another ran low in muscle and a brain area under both long term window regimes. Gene shifts partly matched, partly not. The authors stress that no single diet story fits the ageing body whole.
Catalog record
| CREATOR | Brea J Ford, Anisha Banerjee, Sarah Ding, Anna A Caton, Ashley Grothaus, Sara N Burke, Abbi R Hernandez |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |