Genotypic diversity of multi- and extensively drug-resistant Mycobacterium tuberculosis in Iran: a systematic review and meta-analysis
Mansour Kargarpour Kamakoli, Ehsan Zare BanadKoki, Mehran Nakhaeizadeh, Ava Behrouzi, Nasim Ebrahimifard, Shima Hadifar · 2025
Read Genotypic diversity of multi- and extensively drug-resistant Mycobacterium tuberculosis in Iran: a systematic review and meta-analysis by Mansour Kargarpour Kamakoli, Ehsan Zare BanadKoki, Mehran Nakhaeizadeh, Ava Behrouzi, Nasim Ebrahimifard, Shima Hadifar (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12822001.txt.
Description
Mansour Kargarpour Kamakoli and co-authors pool studies of drug-proof tuberculosis strains across Iran, in a 2025 review. Tracking which genetic families of the TB germ dominate hard cases helps target control efforts. The team searched world and Iranian databases for strain reports on patients whose TB resists many drugs, or nearly all. Thirty-four studies fed the pooled analysis.
Three families led the resistant set: Haarlem, Beijing, and URAL, each claiming roughly a quarter of cases. Several other families appeared only rarely. Most studies covered the multi-drug tier, with fewer on the harder tiers beyond it. Strain maps like this one guide where new tests and drugs will bite hardest. Iran's mix differs from its neighbors, the authors note.
Catalog record
| CREATOR | Mansour Kargarpour Kamakoli, Ehsan Zare BanadKoki, Mehran Nakhaeizadeh, Ava Behrouzi, Nasim Ebrahimifard, Shima Hadifar |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |