Delineation and monitoring of the T cell repertoire of adoptive cell transfer product during the treatment of advanced melanoma
Cameron Kerr, Shirin Soleimani, David T. Mulder, Arash Nabbi, Diana Gray, Stephanie Pedersen, Valentin Sotov, Sumedha Sudhaman, Linh Nguyen, Naoto Hirano, Pamela S. Ohashi, Marcus O. Butler, Trevor J. Pugh · 2025
Read Delineation and monitoring of the T cell repertoire of adoptive cell transfer product during the treatment of advanced melanoma by Cameron Kerr, Shirin Soleimani, David T. Mulder, Arash Nabbi, Diana Gray, Stephanie Pedersen, Valentin Sotov, Sumedha Sudhaman, Linh Nguyen, Naoto Hirano, Pamela S. Ohashi, Marcus O. Butler, Trevor J. Pugh (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12821946.txt.
Description
Kerr and coauthors track immune cells used to treat advanced skin cancer. The care grows a patient own tumor-fighting cells in a lab. Those cells are then put back to attack the tumor. Some patients respond well, while others gain little.
The team read the gene codes of the infused cells in fine detail. They tracked those codes in blood through the full course of care. Their aim was to find cell traits that flag who will benefit. Past clues, such as cell counts, gave mixed results. Clear cell marks could help doctors pick patients and improve the cell product.
Catalog record
| CREATOR | Cameron Kerr, Shirin Soleimani, David T. Mulder, Arash Nabbi, Diana Gray, Stephanie Pedersen, Valentin Sotov, Sumedha Sudhaman, Linh Nguyen, Naoto Hirano, Pamela S. Ohashi, Marcus O. Butler, Trevor J. Pugh |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |