Development of an ELISA Using Recombinant Chimeric SM Protein for Serological Detection of SARS-CoV-2 Antibodies
Gulnur Nakhanova, Olga Chervyakova, Kamshat Shorayeva, Aisha Issabek, Sabina Moldagulova, Asankadyr Zhunushov, Aknur Ulankyzy, Aigerim Zhakypbek, Alisher Omurtay, Aziz Nakhanov, Zharkinay Absatova, Yeraly Shayakhmetov, Kuanysh Jekebekov, Temirlan Baiseit, Aslan Kerimbayev · 2025
Read Development of an ELISA Using Recombinant Chimeric SM Protein for Serological Detection of SARS-CoV-2 Antibodies by Gulnur Nakhanova, Olga Chervyakova, Kamshat Shorayeva, Aisha Issabek, Sabina Moldagulova, Asankadyr Zhunushov, Aknur Ulankyzy, Aigerim Zhakypbek, Alisher Omurtay, Aziz Nakhanov, Zharkinay Absatova, Yeraly Shayakhmetov, Kuanysh Jekebekov, Temirlan Baiseit, Aslan Kerimbayev (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12821618.txt.
Description
Counting who has had COVID, including mild cases never tested, takes blood tests that find antibodies. Gulnur Nakhanova and co-authors built such a test in 2025 around a fused protein, called SM, that joins parts of the virus. They produced the protein in bacteria, purified it, and built an enzyme-linked test that they checked against panels of known positive and negative blood samples, including some drawn before the pandemic.
The test caught about ninety percent of true positives and cleared about ninety-four percent of negatives, with a strong overall accuracy score. The authors present their home-grown kit as ready for tracking population immunity to the virus.
Catalog record
| CREATOR | Gulnur Nakhanova, Olga Chervyakova, Kamshat Shorayeva, Aisha Issabek, Sabina Moldagulova, Asankadyr Zhunushov, Aknur Ulankyzy, Aigerim Zhakypbek, Alisher Omurtay, Aziz Nakhanov, Zharkinay Absatova, Yeraly Shayakhmetov, Kuanysh Jekebekov, Temirlan Baiseit, Aslan Kerimbayev |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |