Fatal Suicide Attempt with Upadacitinib (Rinvoq®) in an Adolescent: A Case Report
Silviya Stoykova, Ivo Ivanov, Evgeniya Byrzashka, Vasil Atanasov · 2025
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Description
Silviya Stoykova, Ivo Ivanov, Evgeniya Byrzashka, and Vasil Atanasov report the first known fatal overdose of upadacitinib, a drug for immune and swelling diseases, in a teen. The drug is seen as safe at set doses, but no fatal dose case had been told before. The report came out in twenty twenty-five.
A girl aged thirteen took a large dose of the drug in tablet form. She fell into deep coma with a very slow heart beat, a full heart block, low blood pressure, low body heat, and acid build up in the blood. Despite strong rescue care, she died within hours. Lab tests on blood and stomach contents found drug levels far above normal care levels.
Catalog record
| CREATOR | Silviya Stoykova, Ivo Ivanov, Evgeniya Byrzashka, Vasil Atanasov |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 19 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |