Could the estrobolome have a role in endometriosis pathogenesis and infertility? A systematic review

Stefania Saponara, Francesco Scicchitano, Maurizio Nicola D’Alterio, Caterina Chilà, Angelos Daniilidis, Salvatore Giovanni Vitale, Stefano Angioni · 2025

Read Could the estrobolome have a role in endometriosis pathogenesis and infertility? A systematic review by Stefania Saponara, Francesco Scicchitano, Maurizio Nicola D’Alterio, Caterina Chilà, Angelos Daniilidis, Salvatore Giovanni Vitale, Stefano Angioni (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12821278.txt.

Description

A gut gene set that handles estrogen is eyed in endometriosis by Stefania Saponara and co-authors in work dated 2025. The ill grows womb-like tissue outside the womb, fed by estrogen, and often blocks fertility. The estrobolome is the set of germ genes that work on estrogen. Five studies passed the team's screen of seven bases. Gut imbalance and estrobolome shifts showed across them.

One enzyme that frees estrogen ran high or awry in some work. Flare marks and awake immune cells rode with the shifts. Germ tuning is a care path worth tests.

Catalog record

CREATORStefania Saponara, Francesco Scicchitano, Maurizio Nicola D’Alterio, Caterina Chilà, Angelos Daniilidis, Salvatore Giovanni Vitale, Stefano Angioni
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE50 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12821278

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