Statistical analysis and simulations that account for simultaneous effects of positive, negative, and no crossover interference in multilocus recombination data

Shaul Sapielkin, Zeev Frenkel, Eyal Privman, Abraham B Korol · 2025

Read Statistical analysis and simulations that account for simultaneous effects of positive, negative, and no crossover interference in multilocus recombination data by Shaul Sapielkin, Zeev Frenkel, Eyal Privman, Abraham B Korol (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12821255.txt.

Description

Shaul Sapielkin and co-authors present a math and computing paper from two thousand twenty-five on how crossovers spread along chromosomes. During cell division, nearby crossovers can push each other apart, cluster together, or act on their own. Older models often miss the clustering case, so fits to real data can be poor.

The team extends an older model so all three patterns can occur at once, and they supply software to fit it. They try the method on real data from a conifer tree, sugar beet, and wheatgrass. The tests show the three kinds of crossover can be told apart on the same chromosome.

Catalog record

CREATORShaul Sapielkin, Zeev Frenkel, Eyal Privman, Abraham B Korol
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE47 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12821255

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