Inverse-designed plasmonic biosensors with LSPR-SPP-wood anomaly coupling enhanced for biomolecular analysis
Yihui Yang, Youqian Chen, Rui Li, Wen Li, Mingqian Chen, Yanan Li, Wenjun Hu, Gang Logan Liu, Liping Huang · 2025
Read Inverse-designed plasmonic biosensors with LSPR-SPP-wood anomaly coupling enhanced for biomolecular analysis by Yihui Yang, Youqian Chen, Rui Li, Wen Li, Mingqian Chen, Yanan Li, Wenjun Hu, Gang Logan Liu, Liping Huang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12821191.txt.
Description
Yihui Yang and co-authors build a highly sensitive biosensor with computer-designed surfaces in a paper from 2025. Studying how molecules bind drives both basic biology and drug discovery. Old methods often lack sensitivity, clean numbers, or simple use.
The new sensor is a layered metasurface with a pattern of tiny cups. A double-goal optimization mixed physics simulations with machine learning to shape it. Three resonance effects team up in the design to sharpen the signal. The result is strong sensitivity with steady readings. Tests on biomolecules showed clean, accurate measures. Such sensors could speed lab work where faint binding signals decide an experiment.
Catalog record
| CREATOR | Yihui Yang, Youqian Chen, Rui Li, Wen Li, Mingqian Chen, Yanan Li, Wenjun Hu, Gang Logan Liu, Liping Huang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 84 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |