Antiphospholipid syndrome presents with aortic thrombosis and central venous catheter-related thrombosis: a case report

Yujiao Chen, Dongjing Li, Yinghong Su, Yulong Zhang · 2025

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Description

Yujiao Chen, Dongjing Li, Yinghong Su, and Yulong Zhang describe a clotting disorder unmasked by heart surgery, in a 2025 case report. A man of thirty-seven had a large, mobile clot in his ascending aorta, removed under a heart-lung machine. Before surgery, tests showed only mild warning signs.

Ten days later, nurses could not pull out his neck catheter: a clot had grown around it despite preventive blood thinners. Force and gentle maneuvers failed, so surgeons removed it openly. Deeper testing revealed widespread vein clots and confirmed antiphospholipid syndrome, an autoimmune condition that drives clotting and had likely caused both events. A heavy combination of steroids, aspirin, warfarin, heparin, and other agents stabilized him. The authors urge suspicion of hidden clotting disorders when clots form fast after surgery, even with near-normal screening tests.

Catalog record

CREATORYujiao Chen, Dongjing Li, Yinghong Su, Yulong Zhang
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE24 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12821187

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