Effects of inactivated COVID-19 vaccination on HIV viremia and reservoir size: a longitudinal cohort study

Jie Li, Caiping Guo, Ruolei Xin, Yuchuan Deng, Can Pang, Jingrong Ye, Jia Li, Hongyan Lu, Xiaoxin He, Quanyi Wang · 2025

Read Effects of inactivated COVID-19 vaccination on HIV viremia and reservoir size: a longitudinal cohort study by Jie Li, Caiping Guo, Ruolei Xin, Yuchuan Deng, Can Pang, Jingrong Ye, Jia Li, Hongyan Lu, Xiaoxin He, Quanyi Wang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12821177.txt.

Description

Jie Li and co-authors study inactivated COVID-19 vaccination in people living with HIV in a 2025 longitudinal cohort study. A key concern was whether vaccination would rebound plasma viral load or change the size of the hidden HIV reservoir, measured as total viral DNA.

Twenty five participants gave blood before vaccination and at several points after each of three doses. Antibody, viral load, viral DNA, and immune cell counts were tracked. The share with undetectable viral load did not change significantly. In those with higher past immune counts, total viral DNA was lower after the third dose than at baseline.

Catalog record

CREATORJie Li, Caiping Guo, Ruolei Xin, Yuchuan Deng, Can Pang, Jingrong Ye, Jia Li, Hongyan Lu, Xiaoxin He, Quanyi Wang
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE32 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12821177

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