Association of glycemic variability with short- and long-term mortality in critically ill patients with trauma
Bing Liu, Jianghua Zhang, Chuangye Song, Jianjun Miao, Xiaowu Li, Jin Wang, Ruichang Lv, Xiaomei Wang, Xiaoning Liu, Guohong Jia · 2025
Read Association of glycemic variability with short- and long-term mortality in critically ill patients with trauma by Bing Liu, Jianghua Zhang, Chuangye Song, Jianjun Miao, Xiaowu Li, Jin Wang, Ruichang Lv, Xiaomei Wang, Xiaoning Liu, Guohong Jia (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12820317.txt.
Description
Bing Liu and co-authors link swinging blood sugar levels to death risk in badly injured patients in intensive care. Steady glucose control is standard after trauma, but how much the level jumps around may matter on its own. The team pulled records for 4,009 adult trauma patients from a large intensive care database. They measured sugar variability across each stay and tracked deaths at thirty days and one year.
Patients with wilder swings died more often in both windows, even after adjusting for other factors. The risk curve bent upward in a J shape, climbing steeply once variability passed roughly twelve percent. The link ran strongest in younger patients and those without diabetes. Sepsis, a runaway infection response, appeared to carry about half to seventy percent of the effect. The authors suggest that smoothing sugar swings, not just lowering the average, deserves a place in trauma care.
Catalog record
| CREATOR | Bing Liu, Jianghua Zhang, Chuangye Song, Jianjun Miao, Xiaowu Li, Jin Wang, Ruichang Lv, Xiaomei Wang, Xiaoning Liu, Guohong Jia |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 60 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |