Photobiomodulation limits oral ulcer development by regulating the immune response

Siying Zhu, Jingfei Fu, Xiaoyan Li, Juan Du, Yi Liu · 2025

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Description

Siying Zhu and four co-authors test whether light therapy can stop mouth ulcers from getting worse. Mouth ulcers are common and sore, and immune cells are thought to drive them. Their 2025 study built an ulcer model in mice, then treated the sores with low-level light.

Stains and cell counts tracked how the sores healed and which immune cells showed up. Light held back the early worsening of ulcers and the swelling around them. Harm-driving cells fell in number, while calm-down cells rose. Helper cells that soothe immune attacks also grew. The authors map a shift in the cell mix toward repair. They say the work backs light as a clinic tool for mouth ulcers.

Catalog record

CREATORSiying Zhu, Jingfei Fu, Xiaoyan Li, Juan Du, Yi Liu
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE39 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12817794

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