First-Generation Antihistamine Use in Geriatric Emergency Department Patients: Retrospective Review
Emily Killen, Michael Cusumano, Zidong Zhang, Richard Newman, Jamie Voigtmann, Angela M. Sanford, Cindy C. Bitter · 2026
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Description
Emily Killen and co-authors review older antihistamine use in emergency care in a study whose text is dated 2025. First-generation antihistamines are common in emergency departments, yet guidelines discourage them in older adults for side effects such as confusion. Whether single doses in the emergency setting carry the same risk as daily use was unclear.
Chart review covered adults sixty-five and older who got such a drug during 2022 at one urban academic center. The drugs appeared in 261 visits, about three percent of older adult visits. Side effects occurred in fifteen percent, most often delirium and urinary retention. Age eighty-five or older and prior cognitive problems raised the risk. Most uses were classed as potentially inappropriate.
Catalog record
| CREATOR | Emily Killen, Michael Cusumano, Zidong Zhang, Richard Newman, Jamie Voigtmann, Angela M. Sanford, Cindy C. Bitter |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 17 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |