Association between high carbohydrate to dietary fiber ratio and risk of dementia in older adults: analysis from the UK biobank

Eunji Lee, Jiyun Hwang, Dong Woo Kim, Byung Yoon Choi, Hee-Joon Bae, Seung Hyun Won, Young Ho Park, SangYun Kim · 2025

Read Association between high carbohydrate to dietary fiber ratio and risk of dementia in older adults: analysis from the UK biobank by Eunji Lee, Jiyun Hwang, Dong Woo Kim, Byung Yoon Choi, Hee-Joon Bae, Seung Hyun Won, Young Ho Park, SangYun Kim (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12814598.txt.

Description

Eunji Lee and seven co-authors linked a carb quality score to dementia risk in older adults in a 2025 study. The score divides daily carbohydrate by fiber, so a high value means refined, fiber-poor eating. Nearly 108,000 British volunteers aged fifty-five and up gave diet recalls and were followed for about twelve years.

Two thousand developed dementia. Rates rose from the lowest to the highest score band, and each standard step up in the score raised risk by about seven percent. Brain scans tied the score to memory region size and cortex thickness as well. The link softened slightly in people with high genetic risk. The authors say swapping refined carbs for fiber may be a simple lever for brain health.

Catalog record

CREATOREunji Lee, Jiyun Hwang, Dong Woo Kim, Byung Yoon Choi, Hee-Joon Bae, Seung Hyun Won, Young Ho Park, SangYun Kim
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE45 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12814598

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