Hydrogen improves the efficacy of tetrandrine in the treatment of silicosis by inhibiting vascular endothelial mesenchymal transition caused by oxidative stress
Kang Xiao, Ming Li, Yingwen Mu, Yuxin Sun, Sirui Wang, Shangya Chen, Jiazi Ma, Mao Cao, Yong Yang, Hua Shao, Xuansheng Ding, Guanqun Cui, Zhongjun Du · 2026
Read Hydrogen improves the efficacy of tetrandrine in the treatment of silicosis by inhibiting vascular endothelial mesenchymal transition caused by oxidative stress by Kang Xiao, Ming Li, Yingwen Mu, Yuxin Sun, Sirui Wang, Shangya Chen, Jiazi Ma, Mao Cao, Yong Yang, Hua Shao, Xuansheng Ding, Guanqun Cui, Zhongjun Du (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12813091.txt.
Description
Kang Xiao and co-authors pair a gas with a drug to treat dust scarred lungs in work dated 2025 in the text. The drug is approved for the illness in China but cannot cure it, and too little of it reaches lung tissue.
In mice, stress driven shifts in lung vessel cells lined up with low drug levels in the lung. Breathing the gas eased both the scarring and the vessel shift, and drug levels in lung tissue rose back up. The team trace the gain to less of a trigger protein reaching vessel cells. The pairing offers a way to make a known drug work harder.
Catalog record
| CREATOR | Kang Xiao, Ming Li, Yingwen Mu, Yuxin Sun, Sirui Wang, Shangya Chen, Jiazi Ma, Mao Cao, Yong Yang, Hua Shao, Xuansheng Ding, Guanqun Cui, Zhongjun Du |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |