Exploring the neuroprotective effects and underlying mechanisms of medical cannabinoids in ischemic stroke: a systematic meta-analysis with bibliometric mapping of cerebral ischemia research
Xiaoqun Li, Lulu Wen, Yun Du, Xinyue Fan, Ningyu Xue, Miao Qu · 2026
Read Exploring the neuroprotective effects and underlying mechanisms of medical cannabinoids in ischemic stroke: a systematic meta-analysis with bibliometric mapping of cerebral ischemia research by Xiaoqun Li, Lulu Wen, Yun Du, Xinyue Fan, Ningyu Xue, Miao Qu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12808455.txt.
Description
Xiaoqun Li and co-authors review medical cannabinoids for ischemic stroke in a paper dated 2025 in its text. Compounds from cannabis have shown protective effects in animal stroke models, but the field's shape and the strength of the proof were unclear. The team mapped the literature and pooled animal studies in one analysis.
Mapping showed steady growth in papers since 2000, with themes around protective mechanisms, disease models, and active compounds. The pooled studies found smaller brain damage, better function scores, and lower swelling, cell death, and inflammation with treatment. Giving a leading compound through the belly over a full course worked best in subgroup checks. The authors call for strong human trials to test whether the animal gains carry over.
Catalog record
| CREATOR | Xiaoqun Li, Lulu Wen, Yun Du, Xinyue Fan, Ningyu Xue, Miao Qu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 68 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |