Feasibility of [15O]H2O PET-CT for quantifying lower limb muscle perfusion in peripheral arterial occlusive disease: a pilot study

Goudje L. van Leeuwen, Richte C. L. Schuurmann, Charalampos Tsoumpas, Milah. N. Baumann, Riemer H. J. A. Slart, Jean-Paul. P. M. de Vries · 2026

Read Feasibility of [15O]H2O PET-CT for quantifying lower limb muscle perfusion in peripheral arterial occlusive disease: a pilot study by Goudje L. van Leeuwen, Richte C. L. Schuurmann, Charalampos Tsoumpas, Milah. N. Baumann, Riemer H. J. A. Slart, Jean-Paul. P. M. de Vries (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12808382.txt.

Description

Van Leeuwen and five colleagues test a scan that measures blood flow in calf muscles in twenty twenty-five. The patients have narrowed leg arteries, which starve muscles of blood and cause pain when walking. Standard tests cannot read flow deep inside the muscle. Their scan uses a short lived form of water as a tracer in a PET camera.

Five patients were scanned before and after a procedure to open the artery. Two ways of outlining the muscle gave steady, repeatable flow values. Scores agreed closely between readers and between repeat reads. Outlining the full muscle worked a bit better than using round sample zones. The team calls the method fit for larger studies.

Catalog record

CREATORGoudje L. van Leeuwen, Richte C. L. Schuurmann, Charalampos Tsoumpas, Milah. N. Baumann, Riemer H. J. A. Slart, Jean-Paul. P. M. de Vries
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE35 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12808382

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