Intraoperative peak lactate as a predictor of in-hospital mortality following non-cardiac emergency surgery: a retrospective cohort study

Yibo Fu, Yuelun Zhang, Le Shen, Yuguang Huang · 2025

Read Intraoperative peak lactate as a predictor of in-hospital mortality following non-cardiac emergency surgery: a retrospective cohort study by Yibo Fu, Yuelun Zhang, Le Shen, Yuguang Huang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12808196.txt.

Description

Emergency surgery patients die in hospital more often than anyone wants, and a number already on the chart during the operation may foretell it. Yibo Fu and co-authors test peak intraoperative lactate in a 2025 study of 2,452 non-cardiac emergency cases at a Beijing hospital. One hundred sixty-one patients died after surgery.

Each step up in peak lactate raised the odds of death by roughly a quarter to a third in adjusted and unadjusted analyses. The pattern held across surgery types and ran stronger in patients with higher anesthesia risk grades. Flexible curve modeling traced the dose shape without forcing it straight. Secondary outcomes covered hospital stay, intensive care time, and ventilation length. The authors propose the peak value as a cheap, early warning already hiding in the record.

Catalog record

CREATORYibo Fu, Yuelun Zhang, Le Shen, Yuguang Huang
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE35 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12808196

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