Intramuscular Promethazine Added to IV Ondansetron for the Prevention of Intrathecal Morphine-Induced Pruritus and Nausea After Cesarean Delivery: A Randomized Controlled Trial
Adam L Wendling, Jonathin N Cates, Cynthia Garvan, Brandon Lopez, M. Anthony Cometa, Matt Andoniadis, Tammy Euliano · 2025
Read Intramuscular Promethazine Added to IV Ondansetron for the Prevention of Intrathecal Morphine-Induced Pruritus and Nausea After Cesarean Delivery: A Randomized Controlled Trial by Adam L Wendling, Jonathin N Cates, Cynthia Garvan, Brandon Lopez, M. Anthony Cometa, Matt Andoniadis, Tammy Euliano (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12807742.txt.
Description
Adam L Wendling and six co-authors test an added drug to ease itching after cesarean birth. Their 2025 trial targets a known side effect of spinal morphine. The morphine controls pain well but often brings itching, nausea, and vomiting. All patients got a standard anti-nausea drug before surgery.
After the cord was clamped, half also got a shot of promethazine, an older sedating drug. The other half got a salt-water dummy shot, with no one told who got what. Sixty-seven patients finished the study. Itching struck sixty-three percent overall and nausea fifteen. The added drug changed none of these rates. Extra itch protection, this trial suggests, needs a different tool.
Catalog record
| CREATOR | Adam L Wendling, Jonathin N Cates, Cynthia Garvan, Brandon Lopez, M. Anthony Cometa, Matt Andoniadis, Tammy Euliano |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 21 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |