Activation of regenerative pathways by exercise intervention in subjects with chronic obstructive pulmonary disease - a study protocol
Caroline Larsson, Linda Elowsson, Ellen Tufvesson, Anna Cederberg, Hugo Öhrneman, Bryan Falcones, Lisa Karlsson, Hamid Akbarshahi, Jaro Ankerst, Leif Bjermer, Andreas Palm, Jakob Löndahl, Andrei Malinovschi, Christer Janson, Margareta Emtner, Gunilla Westergen-Thorsson · 2025
Read Activation of regenerative pathways by exercise intervention in subjects with chronic obstructive pulmonary disease - a study protocol by Caroline Larsson, Linda Elowsson, Ellen Tufvesson, Anna Cederberg, Hugo Öhrneman, Bryan Falcones, Lisa Karlsson, Hamid Akbarshahi, Jaro Ankerst, Leif Bjermer, Andreas Palm, Jakob Löndahl, Andrei Malinovschi, Christer Janson, Margareta Emtner, Gunilla Westergen-Thorsson (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12805779.txt.
Description
Caroline Larsson and co-authors lay out the plan for a study on whether exercise can wake repair pathways in damaged lungs, in a 2025 protocol paper. Chronic obstructive pulmonary disease is usually seen as a one-way decline. Hints that training can improve lung function raise a question: what changes inside the tissue? The team will recruit eighty sedentary adults with stable disease at two centers for twelve weeks of guided training.
Sessions mix aerobic work and muscle strengthening, three times a week, tuned to each person. Tests before and after span lung function, walking and standing capacity, breath gas measures, blood and urine samples, and airway sampling by scope. Two newer lung tests get a validation check along the way. The authors hope the results will name biomarkers and drug targets, and challenge the idea that lung damage cannot turn back.
Catalog record
| CREATOR | Caroline Larsson, Linda Elowsson, Ellen Tufvesson, Anna Cederberg, Hugo Öhrneman, Bryan Falcones, Lisa Karlsson, Hamid Akbarshahi, Jaro Ankerst, Leif Bjermer, Andreas Palm, Jakob Löndahl, Andrei Malinovschi, Christer Janson, Margareta Emtner, Gunilla Westergen-Thorsson |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |