African swine fever vaccine ASFV-G-ΔI177L induces solid protection in four-week-old piglets
Xuan Hanh Tran, Le Thi Thu Phuong, Nguyen Quang Huy, Do Thanh Thuy, Nguyen Van Dung, Lauro Velazquez-Salinas, Elizabeth Ramirez-Medina, Cyril G Gay, Manuel V Borca, Douglas P Gladue · 2025
Read African swine fever vaccine ASFV-G-ΔI177L induces solid protection in four-week-old piglets by Xuan Hanh Tran, Le Thi Thu Phuong, Nguyen Quang Huy, Do Thanh Thuy, Nguyen Van Dung, Lauro Velazquez-Salinas, Elizabeth Ramirez-Medina, Cyril G Gay, Manuel V Borca, Douglas P Gladue (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12804788.txt.
Description
Tran, Gladue, Borca and their co-authors show that a live African swine fever vaccine protects piglets as young as four weeks in 2025. The commercial vaccine had been limited to pigs aged eight to ten weeks, which restricted its use on farms.
Groups of four-week-old pigs got a single shot and were challenged a month later with a virulent field strain from Vietnam. Vaccinated animals stayed clinically normal after the shot, showing no leftover virulence. After challenge, all stayed protected, with no signs of the disease during follow-up. The authors say the age range for use can now widen.
Catalog record
| CREATOR | Xuan Hanh Tran, Le Thi Thu Phuong, Nguyen Quang Huy, Do Thanh Thuy, Nguyen Van Dung, Lauro Velazquez-Salinas, Elizabeth Ramirez-Medina, Cyril G Gay, Manuel V Borca, Douglas P Gladue |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 18 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |