Inhaled amikacin as a preventive strategy against ventilator-associated pneumonia in a trauma intensive care unit: early evidence from a single-center retrospective cohort study
Ohchul Kwon, Nahyeon Lee, Seok Hwa Youn, Younghwan Kim, Mina Kim, Jinho Jheong, Gaesung Ha, Youngwoong Kim · 2025
Read Inhaled amikacin as a preventive strategy against ventilator-associated pneumonia in a trauma intensive care unit: early evidence from a single-center retrospective cohort study by Ohchul Kwon, Nahyeon Lee, Seok Hwa Youn, Younghwan Kim, Mina Kim, Jinho Jheong, Gaesung Ha, Youngwoong Kim (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12800526.txt.
Description
Ohchul Kwon and co-authors check whether breathing in an antibiotic can stop pneumonia in trauma patients on ventilators. Their 2025 study reviews 66 such patients at one centre in 2024. Lung infection tied to the ventilator is a leading harm in intensive care.
Twenty-eight patients got the inhaled drug as prevention and 38 did not. Raw rates of infection looked worse in the treated group. Once the groups were matched and other factors weighed, no real link remained in either direction. Stays and deaths did not differ either. The authors conclude the drug neither prevented nor caused the infections here. They call the evidence early and small, and a larger trial is the clear next step.
Catalog record
| CREATOR | Ohchul Kwon, Nahyeon Lee, Seok Hwa Youn, Younghwan Kim, Mina Kim, Jinho Jheong, Gaesung Ha, Youngwoong Kim |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |