Solvent-induced photophysical properties and stability of clonazepam and Chlordiazepoxide

Roshanak Kian, Mohammad Sadegh Zakerhamidi, Zeynab Ara Merajin · 2025

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Description

Roshanak Kian and co-authors study how the liquid a drug sits in changes its light behavior and shelf life. Their 2025 work covers two anxiety and seizure drugs with ring-shaped parts rich in nitrogen. Both were tested in fourteen liquids that range from water-like to oil-like.

One drug shifted its inner charge far more when lit, shown by a bigger swing in its electric shape. Two math models showed that liquid acidity and basicity drive most of the effect. A new index from the team tracks how well each drug holds up. One drug stayed steadier in oily liquids, the other in water-like ones. The results guide storage and mix choices.

Catalog record

CREATORRoshanak Kian, Mohammad Sadegh Zakerhamidi, Zeynab Ara Merajin
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE40 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12800235

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