One health perspective of antibiotic resistance in enterobacterales from Southeast Asia: a systematic review and meta-analysis

Yewei Xie, Isabelle Maya Srivastava, Fengshi Jing, Chenxinan Ma, Xiangyuan Wu, Ying Chen, Yumeng Du, Xinyi Casuarine Low, Yongjing Ping, Jingxiang Pan, Atharvi Gupta, Nicholas Graves, Yin Mo · 2025

Read One health perspective of antibiotic resistance in enterobacterales from Southeast Asia: a systematic review and meta-analysis by Yewei Xie, Isabelle Maya Srivastava, Fengshi Jing, Chenxinan Ma, Xiangyuan Wu, Ying Chen, Yumeng Du, Xinyi Casuarine Low, Yongjing Ping, Jingxiang Pan, Atharvi Gupta, Nicholas Graves, Yin Mo (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12800116.txt.

Description

Yewei Xie and co-authors published a 2025 review on antibiotic resistance across humans, animals, and the environment in Southeast Asia. Resistance in a large family of gut bacteria threatens health, farming, and ecosystems at once. Efforts under the One Health banner try to treat those fronts as one problem. In this region, the evidence was fragmented.

The team pooled 137 studies from 2013 to 2023. Resistance to a common antibiotic in the gut germ Escherichia coli was highest in human samples, near half, then in environmental samples, and lowest in animals. Resistance to a last-resort drug in another germ reached thirteen percent in humans. Resistance rose over time in both human and animal samples. Two resistance genes appeared in every sector. Most studies came from Thailand and Vietnam, and almost none covered all sectors at once. The authors call the crisis escalating and the research map lopsided.

Catalog record

CREATORYewei Xie, Isabelle Maya Srivastava, Fengshi Jing, Chenxinan Ma, Xiangyuan Wu, Ying Chen, Yumeng Du, Xinyi Casuarine Low, Yongjing Ping, Jingxiang Pan, Atharvi Gupta, Nicholas Graves, Yin Mo
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE36 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12800116

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