Carvacrol-induced apoptosis via tumor suppressor gene activation and oxidative stress modulation in a rat model of breast cancer
Amany Elwakkad, Amina A Gamal el Din, Mohamed A Hebishy, Howida S Abou-Seif · 2025
Read Carvacrol-induced apoptosis via tumor suppressor gene activation and oxidative stress modulation in a rat model of breast cancer by Amany Elwakkad, Amina A Gamal el Din, Mohamed A Hebishy, Howida S Abou-Seif (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12799873.txt.
Description
Elwakkad and three co-authors published an animal study in twenty twenty-five testing carvacrol, a compound from herbs such as oregano, against breast cancer in rats. Earlier lab work hinted the compound can push cancer cells to self-destruct, so the team tested it in living animals.
Female rats were given a chemical that causes breast tumors, then treated with carvacrol by mouth, by injection, or both. The compound switched on genes that guard against tumors and raised signals that drive cell death, while lowering a protein that blocks it. It also cut chemical damage from oxygen stress and helped the liver and kidneys recover. Injection worked best of the three routes. The authors read the results as support for carvacrol as a helper treatment, while noting that dose and delivery need more work before human use.
Catalog record
| CREATOR | Amany Elwakkad, Amina A Gamal el Din, Mohamed A Hebishy, Howida S Abou-Seif |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |