Diabetic Ketoacidosis Associated With the Menstrual Cycle: A Case of Catamenial Diabetic Ketoacidosis
Reza Alavi, Casper Chen, Hector Armando Sanchez Garcia, Obiora Udeozo · 2025
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Description
Alavi and co-authors (2025) present a 34-year-old woman with type 1 diabetes whose dangerous ketoacidosis episodes kept arriving with her menstrual periods. This pattern, called catamenial diabetic ketoacidosis, is uncommon. The team ruled out infection, missed insulin, and pump failure, and her logs showed a clear link between the start of her periods and the attacks.
The likely driver is the hormone shift of the late cycle phase: rising progesterone can push back against insulin and raise blood sugar, tipping the body toward ketone buildup. She was treated with fluids, potassium, and an insulin drip, and within a day her blood chemistry was back to normal and she moved to injected insulin with specialist follow-up. The authors urge clinicians who see repeated unexplained episodes to check the calendar, since steps such as adjusting insulin ahead of the period or smoothing hormone swings may prevent the next attack.
Catalog record
| CREATOR | Reza Alavi, Casper Chen, Hector Armando Sanchez Garcia, Obiora Udeozo |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 9 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |