Sarcopenia risk along the cardiovascular-kidney-metabolic syndrome spectrum: synergistic effects of multisystem burden and physical inactivity

Dingding Wang, Meng Zhang, Qinghua Fan, Jianwen Yu, Jianbo Li, Lanping Jiang, Xunhua Zheng, Siyang Ye, Suchun Li, Peichen Xie, Li Tan, Sixiu Chen, Weixuan Qin, Leigang Jin, Xiaoping Wu, Sydney CW Tang, Yifeng Luo, Wei Chen, Bin Li · 2025

Read Sarcopenia risk along the cardiovascular-kidney-metabolic syndrome spectrum: synergistic effects of multisystem burden and physical inactivity by Dingding Wang, Meng Zhang, Qinghua Fan, Jianwen Yu, Jianbo Li, Lanping Jiang, Xunhua Zheng, Siyang Ye, Suchun Li, Peichen Xie, Li Tan, Sixiu Chen, Weixuan Qin, Leigang Jin, Xiaoping Wu, Sydney CW Tang, Yifeng Luo, Wei Chen, Bin Li (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12797810.txt.

Description

Dingding Wang and co-authors study muscle loss risk across a combined syndrome spectrum in a 2025 paper. Sarcopenia, the steady loss of muscle, drives disability and raises death risk. Heart, kidney, and metabolic problems each feed it, but their joint effect was unmapped.

The analysis uses a national United States survey of more than four thousand adults from 2011 to 2018. A new five-stage framework grades combined heart-kidney-metabolic burden. Muscle loss was judged by a standard national criteria set. Statistical models test how risk grows by stage and whether inactivity multiplies it. The multisystem view may help clinics spot high-risk patients earlier and target activity programs where they count most.

Catalog record

CREATORDingding Wang, Meng Zhang, Qinghua Fan, Jianwen Yu, Jianbo Li, Lanping Jiang, Xunhua Zheng, Siyang Ye, Suchun Li, Peichen Xie, Li Tan, Sixiu Chen, Weixuan Qin, Leigang Jin, Xiaoping Wu, Sydney CW Tang, Yifeng Luo, Wei Chen, Bin Li
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE35 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12797810

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