MARTS-DB: a database of mechanisms and reactions of terpene synthases
Martin Engst, Martin Brokeš, Tereza Čalounová, Raman Samusevich, Roman Bushuiev, Anton Bushuiev, Ratthachat Chatpatanasiri, Adéla Tajovská, Safa Mert Akmeşe, Milana Perković, Matouš Soldát, Josef Sivic, Tomáš Pluskal · 2025
Read MARTS-DB: a database of mechanisms and reactions of terpene synthases by Martin Engst, Martin Brokeš, Tereza Čalounová, Raman Samusevich, Roman Bushuiev, Anton Bushuiev, Ratthachat Chatpatanasiri, Adéla Tajovská, Safa Mert Akmeşe, Milana Perković, Matouš Soldát, Josef Sivic, Tomáš Pluskal (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12797696.txt.
Description
Martin Engst and co-authors release MARTS-DB, a database of the enzymes that build terpenes. Terpenes anchor the terpenoids, nature's largest family of natural products. Published in 2025, the resource answers a data gap. Terpene synthases run some of the most complex reactions in biology, reshaping over half the carbons in their scaffolds. Yet knowledge of their mechanisms sits scattered and hard to compute with.
Curators gathered over 2,850 reactions from 1,432 enzymes across all domains of life. Mechanism maps, drawn step by step, cover more than 500 terpenes. Users can search the collection and download it in machine readable form, and the team invites new contributions. A recent machine learning success in predicting new synthases shows the point of the effort.
Catalog record
| CREATOR | Martin Engst, Martin Brokeš, Tereza Čalounová, Raman Samusevich, Roman Bushuiev, Anton Bushuiev, Ratthachat Chatpatanasiri, Adéla Tajovská, Safa Mert Akmeşe, Milana Perković, Matouš Soldát, Josef Sivic, Tomáš Pluskal |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 20 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |