Hierarchical core–shell DNA condensates enable programmable information storage and encryption

Likang Chu, Liqi Wan, Haixia Wang, Peng Wang, Linyi Deng, Yuan Gao, Pei Guo, Lei He, Da Han · 2025

Read Hierarchical core–shell DNA condensates enable programmable information storage and encryption by Likang Chu, Liqi Wan, Haixia Wang, Peng Wang, Linyi Deng, Yuan Gao, Pei Guo, Lei He, Da Han (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12796251.txt.

Description

Likang Chu, Liqi Wan, Haixia Wang, and a wider team wrote this research paper, published in 2025. It builds a data storage and encryption system out of DNA droplets with a core and shell, using DNA's own programmability to run the needed operations.

DNA stores vast data in tiny space and sips energy, but writing, editing, and locking the data are hard. The team's layered droplets support encoding, erasing, rewriting, copying, and repair of stored information, all while staying easy to read. On top, computing circuits built from biomolecules add encryption tricks: multi-level logic locks, locks that change with time, locks driven by living systems, and fine-grained access control. The authors call it a step toward molecular storage that is both editable and secure, and that can grow to larger scales.

Catalog record

CREATORLikang Chu, Liqi Wan, Haixia Wang, Peng Wang, Linyi Deng, Yuan Gao, Pei Guo, Lei He, Da Han
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE64 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12796251

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