Growth Hormone Response in a Child With a Homozygous TOMM7 Mutation: Novel Therapeutic Insights
Shu Liu, Wei Lu, Lin Yang, Xiubin Tong, Xiu Xu, Huiping Li · 2025
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Description
Shu Liu and five co-authors report a 2025 case of a two-year-old boy in China with a rare gene fault. Both copies of his TOMM7 gene carried the same change, passed down from related parents. The gene keeps a gateway complex in the cell's power plants working, and faults in it cause a syndrome with dwarfism and slow development.
The boy's growth had nearly stopped by age two. From thirty-one months he got long-acting growth hormone shots. Over ten months he grew 3.8 centimeters, and his growth score slid far less than before treatment. The authors offer the case as a lead for treating growth failure tied to faulty cell power plants.
Catalog record
| CREATOR | Shu Liu, Wei Lu, Lin Yang, Xiubin Tong, Xiu Xu, Huiping Li |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 15 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |