Gut Microbiota and Metabolomics Insights into the Gualou-Xiebai Herb Pair for Dyslipidemia and Atherosclerosis

Ni Wang, Yanan Xu, Jiahui Li, Chunsheng Li, Zijian Liu, Zhenglong Li, Yarong Liu, Yexiang Zhang, An Zhou, Hongfei Wu · 2025

Read Gut Microbiota and Metabolomics Insights into the Gualou-Xiebai Herb Pair for Dyslipidemia and Atherosclerosis by Ni Wang, Yanan Xu, Jiahui Li, Chunsheng Li, Zijian Liu, Zhenglong Li, Yarong Liu, Yexiang Zhang, An Zhou, Hongfei Wu (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12790985.txt.

Description

Ni Wang and co-authors test a traditional Chinese herb pair against high blood fats and artery disease in mice. Their 2025 study uses mice bred to develop the disease on a high-fat diet. The herb pair, Gualou-Xiebai, was already known to lower blood lipids in these mice, but whether it works through gut microbes was unclear.

The team read the gut microbe mix and chemical by-products in the mice's cecum contents. Treated mice showed clear shifts in both, tied to better lipid control. The work checks two possible routes: blocking cholesterol uptake and reshaping the gut community. The findings tie a classic remedy to modern gut science.

Catalog record

CREATORNi Wang, Yanan Xu, Jiahui Li, Chunsheng Li, Zijian Liu, Zhenglong Li, Yarong Liu, Yexiang Zhang, An Zhou, Hongfei Wu
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE29 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12790985

Browse the full library · About the Tower of Babel