Effectiveness and cost-effectiveness of a peer-delivered, relational, harm reduction intervention to improve mental health, quality of life, and related outcomes, for people experiencing homelessness and substance use problems: protocol for the ‘SHARPS’ cluster randomised controlled trial
Tessa Parkes, Hannah Carver, Jennifer Boyd, Seonaidh Cotton, Suzanne Breeman, David Cooper, Mark Forrest, Rebecca Foster, Jake Hawthorn, Kate Hunt, Mary Kilonzo, Catriona Matheson, Margaret Maxwell, Stewart W Mercer, Bernie Pauly, Graham Scotland, Wez Steele, Harry Sumnall, Jason Wallace, Lisa Macau · 2025
Read Effectiveness and cost-effectiveness of a peer-delivered, relational, harm reduction intervention to improve mental health, quality of life, and related outcomes, for people experiencing homelessness and substance use problems: protocol for the ‘SHARPS’ cluster randomised controlled trial by Tessa Parkes, Hannah Carver, Jennifer Boyd, Seonaidh Cotton, Suzanne Breeman, David Cooper, Mark Forrest, Rebecca Foster, Jake Hawthorn, Kate Hunt, Mary Kilonzo, Catriona Matheson, Margaret Maxwell, Stewart W Mercer, Bernie Pauly, Graham Scotland, Wez Steele, Harry Sumnall, Jason Wallace, Lisa Macau (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12790120.txt.
Description
Tessa Parkes and co-authors set out a trial of peer guides for homeless people with substance problems in a 2025 protocol. This group often cannot reach the care it needs. An earlier pilot showed guides with lived experience could build trust, lift service use, raise uptake of opioid swap therapy, and cut risky use. A full trial now tests whether the gains hold at scale.
Twenty Salvation Army service towns will be split by coin toss into guide and plain arms. Adults who are homeless or at risk and report problem substance use will be recruited. Cost and value reads ride inside the trial, with a process study alongside. Outcomes span mental health, life quality, and linked service marks. The authors will judge both effect and worth.
Catalog record
| CREATOR | Tessa Parkes, Hannah Carver, Jennifer Boyd, Seonaidh Cotton, Suzanne Breeman, David Cooper, Mark Forrest, Rebecca Foster, Jake Hawthorn, Kate Hunt, Mary Kilonzo, Catriona Matheson, Margaret Maxwell, Stewart W Mercer, Bernie Pauly, Graham Scotland, Wez Steele, Harry Sumnall, Jason Wallace, Lisa Macau |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 73 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |