Comparative Evaluation of Subgingivally Delivered Titanium Prepared Platelet Rich Fibrin (T-PRF) and Tetracycline Fibers as an Adjunct to Scaling and Root Planning in Treatment of Periodontitis: A Randomized Controlled Clinical Trial
Chirag Gupta, Swati Agarwal, Ellora Madan, Kratee Sharma, Nuzla Agha, Karnika Agrawal · 2025
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Description
Gupta, Agarwal, Madan, Sharma, Agha, and Agrawal compare two add-on treatments for gum disease, tested in a randomized trial. Both are placed under the gum line alongside standard deep cleaning. One is a fibrin product made from the patient's blood using titanium tubes. The other is fibers carrying an antibiotic. Their study was published in 2025.
Seventy five sites in adults with chronic gum disease were split into three groups, including cleaning alone. All groups improved over three months on plaque, bleeding, pocket depth, and attachment level. At three months, the antibiotic fiber group generally improved most on bleeding and pocket depth. The authors conclude both add-ons help beyond cleaning alone.
Catalog record
| CREATOR | Chirag Gupta, Swati Agarwal, Ellora Madan, Kratee Sharma, Nuzla Agha, Karnika Agrawal |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 10 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |