Citicoline Oral Solution Induces Functional Enhancement and Synaptic Plasticity in Patients with Open-Angle Glaucoma
Vincenzo Parisi, Lucia Ziccardi, Lucia Tanga, Lucilla Barbano, Emanuele Tinelli, Gianluca Coppola, Antonio Di Renzo, Manuele Michelessi, Gloria Roberti, Carmela Carnevale, Sara Giammaria, Carmen Dell’Aquila, Mattia D’Andrea, Gianluca Manni, Francesco Oddone · 2025
Read Citicoline Oral Solution Induces Functional Enhancement and Synaptic Plasticity in Patients with Open-Angle Glaucoma by Vincenzo Parisi, Lucia Ziccardi, Lucia Tanga, Lucilla Barbano, Emanuele Tinelli, Gianluca Coppola, Antonio Di Renzo, Manuele Michelessi, Gloria Roberti, Carmela Carnevale, Sara Giammaria, Carmen Dell’Aquila, Mattia D’Andrea, Gianluca Manni, Francesco Oddone (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12786903.txt.
Description
Vincenzo Parisi and co-authors tested whether a nerve-supporting supplement improves visual function in glaucoma over a year in a 2025 study. Glaucoma slowly kills the retina's output cells, and pressure control alone does not save every patient's sight. Citicoline, a compound the brain uses to build cell membranes, has been proposed to support the visual pathway itself.
In a randomized prospective study, patients with open-angle glaucoma took an oral citicoline solution for twelve months. Tests of retinal function and signal conduction along the visual pathways tracked the effect. Evidence of true functional gain, not just slower loss, would give doctors an add-on therapy for patients still worsening despite good pressure numbers.
Catalog record
| CREATOR | Vincenzo Parisi, Lucia Ziccardi, Lucia Tanga, Lucilla Barbano, Emanuele Tinelli, Gianluca Coppola, Antonio Di Renzo, Manuele Michelessi, Gloria Roberti, Carmela Carnevale, Sara Giammaria, Carmen Dell’Aquila, Mattia D’Andrea, Gianluca Manni, Francesco Oddone |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |