Microalgae and Macroalgae as Advanced Sources of Tyrosinase Inhibitors
Joanna Harasym, Katarzyna Hałdys · 2025
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Description
Harasym and Hałdys review algae as a source of blockers for tyrosinase, the enzyme that drives pigment making in skin and browning in food. Blocking it safely is wanted in cosmetics, medicine, and farming, but synthetic blockers often bring toxicity or stability problems. Seaweeds and microalgae offer a different pantry. Brown seaweeds yield large tannin-like compounds, one of which blocks the enzyme strongly at tiny doses. Microalgae give small, potent molecules, including one that beat the standard cosmetic blocker kojic acid in tests.
The review explains how the algal compounds grip the enzyme, from slow, two-step binding to tight competitive fits shown by docking studies. It then turns practical: green extraction methods and lipid carrier delivery systems that could keep fragile compounds stable and usable. For product developers, the paper maps both the chemistry and the manufacturing hurdles.
Catalog record
| CREATOR | Joanna Harasym, Katarzyna Hałdys |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 62 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |