Association of Vitamin C Administration with Postoperative Delirium After Cardiac Surgery with Cardiopulmonary Bypass: A Single-Center Retrospective Exploratory Cohort Study †
Yoshihide Kuribayashi, Shigekiyo Matsumoto, Yoshifumi Ohchi, Shinya Kai, Yoshimasa Oyama, Tetsuya Uchino, Osamu Tokumaru, Chihiro Shingu · 2025
Read Association of Vitamin C Administration with Postoperative Delirium After Cardiac Surgery with Cardiopulmonary Bypass: A Single-Center Retrospective Exploratory Cohort Study † by Yoshihide Kuribayashi, Shigekiyo Matsumoto, Yoshifumi Ohchi, Shinya Kai, Yoshimasa Oyama, Tetsuya Uchino, Osamu Tokumaru, Chihiro Shingu (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12786835.txt.
Description
Kuribayashi and co-authors present a 2025 study on vitamin C and delirium after heart surgery. Surgery on a bypass machine stirs oxidative stress, which may breach the brain's barrier and spark confusion. The team compared two groups at one hospital across two time spans. Forty patients got standard care, while forty-four later patients got two grams of vitamin C on arrival in intensive care.
The groups matched on health and surgery factors at the start. Organ trouble and inflammation after surgery looked similar, though one marker ran higher in the vitamin group. Delirium struck the vitamin group far less often, the results show. The authors call the study exploratory and urge a proper trial.
Catalog record
| CREATOR | Yoshihide Kuribayashi, Shigekiyo Matsumoto, Yoshifumi Ohchi, Shinya Kai, Yoshimasa Oyama, Tetsuya Uchino, Osamu Tokumaru, Chihiro Shingu |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |