Therapeutic Plasma Exchange in COVID-19-Associated Sepsis: IL-6 Dynamics, Inflammatory Phenotypes, and Short-Term Organ-Failure Trajectories in a Real-World Cohort
Nicoleta Sgavardea, Dorel Sandesc, Tamara Mirela Porosnicu, Ovidiu Bedreag, Ciprian Gîndac, Marius Papurica, Elena Hogea, Patricia Hogea, Iulia Georgiana Bogdan, Voichita Elena Lazureanu · 2025
Read Therapeutic Plasma Exchange in COVID-19-Associated Sepsis: IL-6 Dynamics, Inflammatory Phenotypes, and Short-Term Organ-Failure Trajectories in a Real-World Cohort by Nicoleta Sgavardea, Dorel Sandesc, Tamara Mirela Porosnicu, Ovidiu Bedreag, Ciprian Gîndac, Marius Papurica, Elena Hogea, Patricia Hogea, Iulia Georgiana Bogdan, Voichita Elena Lazureanu (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12786558.txt.
Description
Nicoleta Sgavardea and colleagues examine whether filtering the blood calms the cytokine storm of severe COVID-19 sepsis. Plasma exchange is a rescue move meant to wash out inflammatory drivers. The team reviewed 102 ventilated patients who got at least one session.
The key marker IL-6 fell after treatment in every group, whether patients had one session or several. More sessions did not clearly beat fewer, and timing mattered little in the data. A clotting marker, D-dimer, dropped mainly after single sessions. The authors sorted patients into inflammation types to hunt for who benefits most, a question still open.
Catalog record
| CREATOR | Nicoleta Sgavardea, Dorel Sandesc, Tamara Mirela Porosnicu, Ovidiu Bedreag, Ciprian Gîndac, Marius Papurica, Elena Hogea, Patricia Hogea, Iulia Georgiana Bogdan, Voichita Elena Lazureanu |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |