Why Does Mucoadhesion Matter? Mucoadhesive Drug Delivery Systems with Antifungal Activity in the Local Treatment of Oral Cavity Candidiasis
Katarzyna Olechno, Julia Higuchi, Katarzyna Winnicka · 2025
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Description
Katarzyna Olechno, Julia Higuchi, and Katarzyna Winnicka review sticky drug forms for oral fungal infection in a 2025 paper. Fungal mouth disease challenges patients with weak immunity most. Cancer therapy and antibiotics also raise the risk. Local treatment beats systemic dosing when it stays in place.
Forms that cling to wet mouth tissue hold drug at the infection site. Longer retention means adequate levels with lower doses. Fewer side effects and better patient compliance follow. Few such products actually reach the market, though. The review explains how mucoadhesion works mechanically and chemically. Polymers that deliver the stickiness are cataloged. Recent development reports and quality tests are surveyed. Conventional forms wash away too fast in the moist mouth. Optimal adhesion is framed as the key design problem. The paper maps a formulation agenda for oral candidiasis.
Catalog record
| CREATOR | Katarzyna Olechno, Julia Higuchi, Katarzyna Winnicka |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 92 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |