Effects of Luteolin and Apigenin on Adipogenesis Markers PPARγ and FABP4 and Thermogenesis Marker UCP1 in 3T3-L1 Preadipocyte Cell Line
Gülcan Uysal Yeler, Ayşegül Sivaslıoğlu, Tuğba Gülsün, Zeynep Göktaş · 2025
Read Effects of Luteolin and Apigenin on Adipogenesis Markers PPARγ and FABP4 and Thermogenesis Marker UCP1 in 3T3-L1 Preadipocyte Cell Line by Gülcan Uysal Yeler, Ayşegül Sivaslıoğlu, Tuğba Gülsün, Zeynep Göktaş (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12786047.txt.
Description
Uysal Yeler and co-authors studied two plant compounds in fat cells grown in the lab, in a paper published in 2025. The compounds are natural pigments found in herbs and vegetables. The team asked how they affect the making of fat cells and the burning of fat for heat. One master switch drives fat cell growth, and it turns on a partner protein as cells mature. A third protein, found in heat-making fat, lets cells waste energy as warmth.
The researchers dosed mouse fat precursor cells with each compound at three strengths during their maturation. They then measured the switch, its partner, and the heat protein, as both gene activity and protein levels. Shifts in the first two would signal slower fat making. A rise in the heat protein would signal more energy burning. The results inform the search for plant-based aids against obesity.
Catalog record
| CREATOR | Gülcan Uysal Yeler, Ayşegül Sivaslıoğlu, Tuğba Gülsün, Zeynep Göktaş |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 20 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |