Mechanisms of Dural Involvement in Cerebral Amyloid Angiopathy
Marialuisa Zedde, Fabrizio Piazza, Rosario Pascarella · 2025
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Description
Marialuisa Zedde, Fabrizio Piazza, and Rosario Pascarella wrote a review from 2025 on an overlooked corner of a brain vessel disease. The disease lays a protein called amyloid into the walls of small brain vessels, mostly in older people. It is known for causing bleeding in the brain's outer lobes and for driving decline in thinking. The review turns to the dura, the tough sac around the brain, and its lymph vessels.
Those lymph vessels may drain amyloid out of the brain with the fluid that bathes it. If that drainage falters, amyloid could pile up faster and worsen the disease. The review also weighs the disease's link with bleeding under the dura. Such bleeds may signal a higher risk of further bleeding events. Fragile vessel walls and chronic swelling are offered as the ties. The authors frame the dura as a possible route for future treatments.
Catalog record
| CREATOR | Marialuisa Zedde, Fabrizio Piazza, Rosario Pascarella |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 59 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |