Beyond Leptin and Adiponectin: The Diverse Roles of Adipokines in the Myocardial Hypertrophic Process and Heart Failure and Their Potential Contribution in Obesity
Morris Karmazyn, Xiaohong Tracey Gan · 2025
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Description
Morris Karmazyn and Xiaohong Tracey Gan review adipokines that go past leptin and adiponectin. Their 2025 review centres on thickening of heart muscle and on heart failure. It asks how these fat-linked signals may count, most of all in obesity.
Fat cells let out many compounds that act in the body, and they move in the blood to far organs. Other tissues make them too, and the heart is one such tissue. These factors can shape how the heart works and how it meets disease. Their effects on the heart as it is remade, through hypertrophy and fibrosis, can help or harm. Which way they act rests on the type of adipokine. The team notes a web of signals, and a balance of forces for or against such change. Just how much each factor adds to heart disease is still not clear.
Catalog record
| CREATOR | Morris Karmazyn, Xiaohong Tracey Gan |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 73 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |