Interactive Effects of Genetic Susceptibility and Early-Life Tobacco Smoke Exposure on the Asthma–Eczema Complex Phenotype in Children: 6-Year Follow-Up Case-Control Study

Anna Dębińska, Hanna Danielewicz, Anna Drabik-Chamerska, Barbara Sozańska · 2025

Read Interactive Effects of Genetic Susceptibility and Early-Life Tobacco Smoke Exposure on the Asthma–Eczema Complex Phenotype in Children: 6-Year Follow-Up Case-Control Study by Anna Dębińska, Hanna Danielewicz, Anna Drabik-Chamerska, Barbara Sozańska (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12785580.txt.

Description

Anna Dębińska, Hanna Danielewicz, Anna Drabik-Chamerska, and Barbara Sozańska studied how genes and smoke together shape childhood allergy disease in this 2025 paper. Asthma and eczema often arrive as a pair, a combined pattern thought to grow from shared genes plus early-life surroundings.

The team followed 188 children from before age two to age six. All had doctor-confirmed eczema or asthma status, and parents reported tobacco smoke exposure at home in the early years. DNA tests read two genes flagged by an earlier genome-wide study of gene-environment interplay. The question was whether those gene variants raise the risk of eczema or the combined pattern, and whether smoke exposure bends that risk. Such interplay studies point to which children most need smoke-free homes.

Catalog record

CREATORAnna Dębińska, Hanna Danielewicz, Anna Drabik-Chamerska, Barbara Sozańska
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE42 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12785580

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