Safety and Pharmacogenetics of Oxycodone in Post-Cesarean Analgesia and Breastfeeding Dyads: A Proactive Approach to Precision Medicine

Snehi Shetal Shah, Hsing-Hua Sylvia Lin, Sauren Baheti, Erin Bundock, Alex Anderson, Rose Barlow, Barkha Patel, Linda Park, Senthilkumar Sadhasivam · 2025

Read Safety and Pharmacogenetics of Oxycodone in Post-Cesarean Analgesia and Breastfeeding Dyads: A Proactive Approach to Precision Medicine by Snehi Shetal Shah, Hsing-Hua Sylvia Lin, Sauren Baheti, Erin Bundock, Alex Anderson, Rose Barlow, Barkha Patel, Linda Park, Senthilkumar Sadhasivam (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12785532.txt.

Description

Snehi Shah and co-authors check oxycodone safety for new mothers and their breastfed babies. Their 2025 study enrolls more than two hundred mother-infant pairs after cesarean birth under a stingy opioid plan. A gene that steers opioid breakdown, CYP2D6, was typed to test its role in side effects. Most mothers took opioids in hospital, at set low doses as needed.

No mother suffered slowed breathing, and nausea hit a modest share. A similar share of babies showed a bundle of watched side effects. Heavier in-hospital use tracked higher baby risk at the edge of significance. Fast gene types leaned worse, short of proof. Lowest doses are urged.

Catalog record

CREATORSnehi Shetal Shah, Hsing-Hua Sylvia Lin, Sauren Baheti, Erin Bundock, Alex Anderson, Rose Barlow, Barkha Patel, Linda Park, Senthilkumar Sadhasivam
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE31 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12785532

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