Assessment of Local and Metastatic Recurrence Following Robot-Assisted Radical Prostatectomy by Margin Status Using PSMA PET/CT Scan
Thomas Edward Ahlering, Yeagyeong Hwang, Michael Matthew Lee, Joshua Tran, Anders David Jens Carlson, Levon Kazarian, Karren Liang, Whitney Zhang · 2025
Read Assessment of Local and Metastatic Recurrence Following Robot-Assisted Radical Prostatectomy by Margin Status Using PSMA PET/CT Scan by Thomas Edward Ahlering, Yeagyeong Hwang, Michael Matthew Lee, Joshua Tran, Anders David Jens Carlson, Levon Kazarian, Karren Liang, Whitney Zhang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12785039.txt.
Description
Thomas Ahlering and co-authors test whether surgical margin status predicts where prostate cancer returns, in this 2025 Europe PMC paper. After radical prostatectomy, local recurrence is usually blamed on leftover tissue at positive margins. Yet most men with positive margins never see their cancer markers rise again. The team used PSMA PET scans, which can locate recurrence, in men whose markers had risen.
Among one hundred fifty-nine men, local recurrence rates were similar for negative and positive margin groups, as were lymph node and bone spread rates. Statistical models found margin status did not predict local recurrence. The results challenge the assumption that margins alone explain where disease comes back.
Catalog record
| CREATOR | Thomas Edward Ahlering, Yeagyeong Hwang, Michael Matthew Lee, Joshua Tran, Anders David Jens Carlson, Levon Kazarian, Karren Liang, Whitney Zhang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 20 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |