Transformer-Based Classification of Transposable Element Consensus Sequences with TEclass2

Lucas Bickmann, Matias Rodriguez, Xiaoyi Jiang, Wojciech Makałowski · 2025

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Description

Lucas Bickmann, Matias Rodriguez, Xiaoyi Jiang, and Wojciech Makałowski introduce a tool that sorts jumping genes by type, in a 2025 paper. Jumping genes are DNA stretches that copy and move within a genome. They make up a large share of many genomes and shape how genomes evolve. Their variety makes them hard to sort with older tools.

Their tool, TEclass2, uses a lean transformer model that reads DNA in short chunks. It sorts shared sequence forms into sixteen families. Tests show it sorts more accurately than earlier tools, and users can retrain it on their own data. A web version with ready models makes it quick to use. The authors aim to strengthen genome notes for many research groups.

Catalog record

CREATORLucas Bickmann, Matias Rodriguez, Xiaoyi Jiang, Wojciech Makałowski
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE33 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12785036

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