Systematic Identification of the Serine Protease Family (StSPs) and Functional Characterization of the Secretory Protein StSP8-4 for Pathogenicity in Setosphaeria turcica
Qihui Zhou, Xiaodong Gong, Jingjing Zhang, He Zhou, Mengfang Zhu, Bin Hu, Jingao Dong, Yuwei Liu, Shouqin Gu · 2025
Read Systematic Identification of the Serine Protease Family (StSPs) and Functional Characterization of the Secretory Protein StSP8-4 for Pathogenicity in Setosphaeria turcica by Qihui Zhou, Xiaodong Gong, Jingjing Zhang, He Zhou, Mengfang Zhu, Bin Hu, Jingao Dong, Yuwei Liu, Shouqin Gu (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12784987.txt.
Description
Qihui Zhou and co-authors catalogue a family of cutting enzymes in a fungus that blights maize. Serine proteases help fungi grow and infect, but this family was unmapped in Setosphaeria turcica. Genome analysis found 74 family members falling into 12 subfamilies. Twenty-four carry signal tags marking them for export from the cell, and yeast tests confirmed five truly are secreted. Gene activity data showed most of the family switching on during key infection stages.
One exported member, StSP8-4, rose strongly during infection. Strains with the gene boosted or silenced showed it is needed for full disease power, though silencing it did not harm the fungus's spores or threads. The authors present the catalogue, and this gene in particular, as groundwork for understanding and eventually blunting the blight.
Catalog record
| CREATOR | Qihui Zhou, Xiaodong Gong, Jingjing Zhang, He Zhou, Mengfang Zhu, Bin Hu, Jingao Dong, Yuwei Liu, Shouqin Gu |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |