Potential Role of Serum Cytokines and Chemokines as Biomarkers of Injury Severity and Functional Outcomes Following Pediatric Traumatic Brain Injury

Kathryn Swaby, Alexander J. Skirvin, Natalie Machado, Maria Mateo Chavez, Julia Alexis Bernal, Ana Fuentes, Charlene P. Pringle, Kourtney Guthrie, Jennifer Coto, Rajderkar Dhanashree, Joslyn Gober, Paula Karina Perez, Juan P. Solano, Heather J. McCrea, Ricardo Loor-Torres, Joyce Kaufman, Ayham Alkha · 2025

Read Potential Role of Serum Cytokines and Chemokines as Biomarkers of Injury Severity and Functional Outcomes Following Pediatric Traumatic Brain Injury by Kathryn Swaby, Alexander J. Skirvin, Natalie Machado, Maria Mateo Chavez, Julia Alexis Bernal, Ana Fuentes, Charlene P. Pringle, Kourtney Guthrie, Jennifer Coto, Rajderkar Dhanashree, Joslyn Gober, Paula Karina Perez, Juan P. Solano, Heather J. McCrea, Ricardo Loor-Torres, Joyce Kaufman, Ayham Alkha (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12784923.txt.

Description

Kathryn Swaby and co-authors report an early study from two thousand twenty-five on blood markers after brain injury in children. Traumatic brain injury is a leading cause of death and disability in the young. Doctors still lack blood tests that judge severity and forecast recovery with confidence, so the team tested immune signal proteins.

They measured many cytokines and chemokines in blood from twenty-six injured children and twenty-one controls. Several signals were higher after injury, and a few were lower. Two signals at enrollment tracked severe injury very closely. A handful of signals also linked to poor function over the following year. The authors treat the results as exploratory, pointing to candidates for larger confirmatory studies.

Catalog record

CREATORKathryn Swaby, Alexander J. Skirvin, Natalie Machado, Maria Mateo Chavez, Julia Alexis Bernal, Ana Fuentes, Charlene P. Pringle, Kourtney Guthrie, Jennifer Coto, Rajderkar Dhanashree, Joslyn Gober, Paula Karina Perez, Juan P. Solano, Heather J. McCrea, Ricardo Loor-Torres, Joyce Kaufman, Ayham Alkha
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE35 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12784923

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